Beta hemoglobinopathies, includes sickle cell disease and beta thalassemias: Beta hemoglobinopathies, including sickle cell disease and beta thalassemia, are autosomal recessive disorders of red blood cells with variable severity and age of onset. Clinical feats the potential clinical and/or reprlicable, this individual&apos;s partner. If this individual&apos;s reproductive partner is also a carrier of a mutation in the same gene the risk for an affected fetus is xxxxx%. 

Cystic fibrosis: Cystic fibrosis (CF) is an autosomal recessive disease with variable severity and age of onset. Symptoms of classic CF include elevated sweat chloride levels, progressive lung disease, pancreatic insufficiency, and male infertility. Individuals with mild CF may have pancreatic sufficiency. CFTR-related  when it occurs with 7T. PolyT variant analysis may, therefore, provide additional information. Genetic counseling is recommended to discuss the potential clinical and/or reproductive implications of these results, as well as recommendavidual&apos;s reproductive partner is a carrier of a mutation in the same gene the risk for an affected fetus is xxxx%. 

Spinal muscular atrophy: Spinal muscular atrophy (SMA) is an autosomal recessive disease with variable age of onset and severity caused by mutations in the SMN1 gene. Individuals with one copy of SMN1 are predicted to be carriers of SMA; those with two or more copies have a reduced carrier risk. Approximately 0% of affected individuals have 0 copies of SMN1. In individuals with 0 copies of SMN1 an incnumber of copies of the SMN2 gene correlates with reduced disease severity indings  include congenital joint contractures, polyhydramnios, and decreased fetal movement (Korinthenberg, PMID:XXXXX). Treatment is supportive. 

Fragile X syndrome: Fragile X syndrome, also known as, is an X-linked disease of intellectual disability with variable severity caused by mutations in the FMR1 gene. dasd% of mutations are expansions repeat sequences. Rare mutations include missense mutations and gene deletions. Interpretation of repeat expansion results is based on the following rangng, narrow face with prominent ears, joint laxity, and flat feet. Treatment is supportive and focuses on educational and behavioral support and management of symptoms. (So, PMID:XXXXXX).